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Associate Professor, College of Chemistry, Central China Normal University (2014-present)
Associate Professor, College of Plant Science & Technology, Huazhong Agricultural University
(2013-2014)
Post Doc. College of Life, Nan jingUniversity & Jiangsu Simcere Pharmaceutical R&D Co., Ltd.
(2009-2013)
Ph.D. College of Chemistry, Central China Normal University (Dec 2008).
B.A. Department of Chemistry, Anqing Normal University (Jun 2002).
Research Fields and Interests
Medicinal chemistry, Drug/pesticide discovery.
Selected Publications
1. Wang, Y. Z.; *Huang, W.; *Xin, M. H.; Chen, P.; Gui, L.; Zhao, X. E.; Tang, F.; Wang, J.; Liu, F.;*
Identification of 4-(2-furanyl) pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg. Med. Chem. 2016, 24, accepted. (共同通讯作者)
2. Hao, G. F.;† Yang, S. G.;† Huang, W.;† Wang, L.; Shen, Y. Q.; Tu, W. L.; Li, H.; Huang, L. S.; Wu, J. W.;Berry, E. A.; Yang, G. F.* Discovery of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitors by Computational Substitution Optimization. Sci. Rep. 2015, 13471.(†共同第一作者)
3. Zhao, X. E.;† Huang, W.;† Wang, Y. Z.; Xin, M. H.; Jin, Q.; Cai, J. F.; Tang, F.; Zhao, Y.; Xiang, H.* Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors. Bioorg.Med. Chem. 2015, 23, 4344-4353. (†共同第一作者)
4. Zhao, X. E.;† Huang, W.;† Wang, Y. Z.; Xin, M. H.; Jin, Q.; Cai, J. F.; Tang, F.; Zhao, Y.; Xiang, H.* Discovery of Novel Bruton’s Tyrosine Kinase (BTK) Inhibitors Bearing a Pyrrolo [2,3-d] pyrimidine Scaffold. Bioorg. Med. Chem. 2015, 23, 891-901. (†共同第一作者)
5. She, N. F.; Zhuo, L. S.; Jiang, W.; Zhu, X. L.;Wang, J.; Ming, Z. H.; Zhao, X. E.; Cong, X.;Huang, W.*; Design, Synthesis and Evaluation of Highly Selective Pyridone-based Class II MET Inhibitors. Bioorg. Med. Chem. Lett.2014, 24, 3351-3355.
6. Huang, W.; Chen, Q.; Yang, W. C.; Yang, G. F.* Efficient Synthesis and Antiproliferative Activity of Novel Thioether-Substituted Flavonoids. Eur. J. Med. Chem. 2013, 66, 161-170.
7. Huang, W.; Zhao, X. E.; Cai, J. F.; Wang, J.; Cong, X.; Ye, J.; Fused heterocyclic derivatives and uses thereof. 28/12/2012, PCT International Patent. WO2013097753.
8. Huang, W.; Cong, X.; Zhao, X. E.; Ming, Z. H.; Ye, J.; Wang, J.; Yuan, Y. 2,7-naphthyridine derivatives, preparation and uses thereof. 20/01/2012, PCTInternational Patent.WO2013033981.
9. Jin, Q.; Huang, W.; Wang, Y. Z.; Zhao, X. E.; Cai, J. F.; Yang, J.; Tang, F.; Zhao, Y.; Zhu, J. P. Bruton’styrosine kinase inhibitorf. 15/05/2014, PCT International Patent. WO2014187262.
Honors and Awards
4th Award for Youth Science & Technology Innovation of China (2007)
